Medicines on the FDA drug shortage list, with which forms and strengths are affected, who makes them and when supply is expected back.
161 medicines
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Ciprofloxacin Hydrochloride and Hydrocortisone Being discontinued 1 product · updated October 30, 2026
Anti-Infective
Product Availability Expected supply / notes Cipro, Otic Suspension/Drops, 0.2% base, 1% (NDC 66758-087-70)
Sandoz Inc.Discontinuation of the manufacturing of NDC 66758-087-70. Authorized generic is available under new NDC 0781-6218-70
Being discontinued · October 30, 2026 -
Metformin Hydrochloride Being discontinued 2 products · updated October 22, 2026
Endocrinology/Metabolism
Product Availability Expected supply / notes Metformin Hydrochloride, Tablet, Extended Release, 500 mg (NDC 0378-6002-91)
Mylan Pharmaceuticals Inc., a Viatris CompanyA business decision was made was discontinue manufacture of the drug product.
Being discontinued · October 22, 2026Metformin Hydrochloride, Tablet, Extended Release, 1000 mg (NDC 0378-6001-91)
Mylan Pharmaceuticals Inc., a Viatris CompanyA business decision was made was discontinue manufacture of the drug product.
Being discontinued · October 22, 2026 -
Enoxaparin Sodium Being discontinued 24 products · updated October 20, 2026
Hematology
Product Availability Expected supply / notes Lovenox, Injection, 60 mg/.6 mL (NDC 0075-0621-60)
Sanofi-Aventis U.S. LLCDiscontinuation of the manufacture of the drug for the U.S. market. This decision is not related to product safety or quality concerns. FDA-approved generic enoxaparin products and other treatment options are available. Remaining inventory may continue to be available through wholesalers and other distribution channels until existing supplies are depleted. Availability may vary by presentation with last lot expected to expire in March 2029.
Being discontinued · October 20, 2026Lovenox, Injection, 300 mg/3 mL (NDC 0075-8030-01)
Sanofi-Aventis U.S. LLCDiscontinuation of the manufacture of the drug for the U.S. market. This decision is not related to product safety or quality concerns. FDA-approved generic enoxaparin products and other treatment options are available. Remaining inventory may continue to be available through wholesalers and other distribution channels until existing supplies are depleted. Availability may vary by presentation with last lot expected to expire in March 2029.
Being discontinued · October 20, 2026Lovenox, Injection, 150 mg/1 mL (NDC 0075-2915-01)
Sanofi-Aventis U.S. LLCDiscontinuation of the manufacture of the drug for the U.S. market. This decision is not related to product safety or quality concerns. FDA-approved generic enoxaparin products and other treatment options are available. Remaining inventory may continue to be available through wholesalers and other distribution channels until existing supplies are depleted. Availability may vary by presentation with last lot expected to expire in March 2029.
Being discontinued · October 20, 2026Lovenox, Injection, 40 mg/.4 mL (NDC 0075-8014-10)
Sanofi-Aventis U.S. LLCDiscontinuation of the manufacture of the drug for the U.S. market. This decision is not related to product safety or quality concerns. FDA-approved generic enoxaparin products and other treatment options are available. Remaining inventory may continue to be available through wholesalers and other distribution channels until existing supplies are depleted. Availability may vary by presentation with last lot expected to expire in March 2029.
Being discontinued · October 20, 2026Lovenox, Injection, 80 mg/.8 mL (NDC 0075-0622-80)
Sanofi-Aventis U.S. LLCDiscontinuation of the manufacture of the drug for the U.S. market. This decision is not related to product safety or quality concerns. FDA-approved generic enoxaparin products and other treatment options are available. Remaining inventory may continue to be available through wholesalers and other distribution channels until existing supplies are depleted. Availability may vary by presentation with last lot expected to expire in March 2029.
Being discontinued · October 20, 2026Enoxaparin Sodium, Injection, 30 mg/.3 mL (NDC 0955-1003-10)
Sanofi-Aventis U.S. LLCDiscontinuation of the manufacture of the drug for the U.S. market. This decision is not related to product safety or quality concerns. FDA-approved generic enoxaparin products and other treatment options are available. Remaining inventory may continue to be available through wholesalers and other distribution channels until existing supplies are depleted. Availability may vary by presentation with last lot expected to expire in March 2029.
Being discontinued · October 20, 2026Lovenox, Injection, 30 mg/.3 mL (NDC 0075-0624-30)
Sanofi-Aventis U.S. LLCDiscontinuation of the manufacture of the drug for the U.S. market. This decision is not related to product safety or quality concerns. FDA-approved generic enoxaparin products and other treatment options are available. Remaining inventory may continue to be available through wholesalers and other distribution channels until existing supplies are depleted. Availability may vary by presentation with last lot expected to expire in March 2029.
Being discontinued · October 20, 2026Enoxaparin Sodium, Injection, 60 mg/.6 mL (NDC 0955-1006-10)
Sanofi-Aventis U.S. LLCDiscontinuation of the manufacture of the drug for the U.S. market. This decision is not related to product safety or quality concerns. FDA-approved generic enoxaparin products and other treatment options are available. Remaining inventory may continue to be available through wholesalers and other distribution channels until existing supplies are depleted. Availability may vary by presentation with last lot expected to expire in March 2029.
Being discontinued · October 20, 2026Lovenox, Injection, 80 mg/.8 mL (NDC 0075-8018-10)
Sanofi-Aventis U.S. LLCDiscontinuation of the manufacture of the drug for the U.S. market. This decision is not related to product safety or quality concerns. FDA-approved generic enoxaparin products and other treatment options are available. Remaining inventory may continue to be available through wholesalers and other distribution channels until existing supplies are depleted. Availability may vary by presentation with last lot expected to expire in March 2029.
Being discontinued · October 20, 2026Lovenox, Injection, 30 mg/.3 mL (NDC 0075-8013-10)
Sanofi-Aventis U.S. LLCDiscontinuation of the manufacture of the drug for the U.S. market. This decision is not related to product safety or quality concerns. FDA-approved generic enoxaparin products and other treatment options are available. Remaining inventory may continue to be available through wholesalers and other distribution channels until existing supplies are depleted. Availability may vary by presentation with last lot expected to expire in March 2029.
Being discontinued · October 20, 2026Enoxaparin Sodium, Injection, 120 mg/.8 mL (NDC 0955-1012-10)
Sanofi-Aventis U.S. LLCDiscontinuation of the manufacture of the drug for the U.S. market. This decision is not related to product safety or quality concerns. FDA-approved generic enoxaparin products and other treatment options are available. Remaining inventory may continue to be available through wholesalers and other distribution channels until existing supplies are depleted. Availability may vary by presentation with last lot expected to expire in March 2029.
Being discontinued · October 20, 2026Lovenox, Injection, 60 mg/.6 mL (NDC 0075-8016-10)
Sanofi-Aventis U.S. LLCDiscontinuation of the manufacture of the drug for the U.S. market. This decision is not related to product safety or quality concerns. FDA-approved generic enoxaparin products and other treatment options are available. Remaining inventory may continue to be available through wholesalers and other distribution channels until existing supplies are depleted. Availability may vary by presentation with last lot expected to expire in March 2029.
Being discontinued · October 20, 2026Enoxaparin Sodium, Injection, 100 mg/1 mL (NDC 0955-1010-10)
Sanofi-Aventis U.S. LLCDiscontinuation of the manufacture of the drug for the U.S. market. This decision is not related to product safety or quality concerns. FDA-approved generic enoxaparin products and other treatment options are available. Remaining inventory may continue to be available through wholesalers and other distribution channels until existing supplies are depleted. Availability may vary by presentation with last lot expected to expire in March 2029.
Being discontinued · October 20, 2026Lovenox, Injection, 120 mg/.8 mL (NDC 0075-8022-10)
Sanofi-Aventis U.S. LLCDiscontinuation of the manufacture of the drug for the U.S. market. This decision is not related to product safety or quality concerns. FDA-approved generic enoxaparin products and other treatment options are available. Remaining inventory may continue to be available through wholesalers and other distribution channels until existing supplies are depleted. Availability may vary by presentation with last lot expected to expire in March 2029.
Being discontinued · October 20, 2026Lovenox, Injection, 100 mg/1 mL (NDC 0075-8020-10)
Sanofi-Aventis U.S. LLCDiscontinuation of the manufacture of the drug for the U.S. market. This decision is not related to product safety or quality concerns. FDA-approved generic enoxaparin products and other treatment options are available. Remaining inventory may continue to be available through wholesalers and other distribution channels until existing supplies are depleted. Availability may vary by presentation with last lot expected to expire in March 2029.
Being discontinued · October 20, 2026Lovenox, Injection, 300 mg/3 mL (NDC 0075-0626-03)
Sanofi-Aventis U.S. LLCDiscontinuation of the manufacture of the drug for the U.S. market. This decision is not related to product safety or quality concerns. FDA-approved generic enoxaparin products and other treatment options are available. Remaining inventory may continue to be available through wholesalers and other distribution channels until existing supplies are depleted. Availability may vary by presentation with last lot expected to expire in March 2029.
Being discontinued · October 20, 2026Enoxaparin Sodium, Injection, 150 mg/1 mL (NDC 0955-1015-10)
Sanofi-Aventis U.S. LLCDiscontinuation of the manufacture of the drug for the U.S. market. This decision is not related to product safety or quality concerns. FDA-approved generic enoxaparin products and other treatment options are available. Remaining inventory may continue to be available through wholesalers and other distribution channels until existing supplies are depleted. Availability may vary by presentation with last lot expected to expire in March 2029.
Being discontinued · October 20, 2026Lovenox, Injection, 150 mg/1 mL (NDC 0075-8025-10)
Sanofi-Aventis U.S. LLCDiscontinuation of the manufacture of the drug for the U.S. market. This decision is not related to product safety or quality concerns. FDA-approved generic enoxaparin products and other treatment options are available. Remaining inventory may continue to be available through wholesalers and other distribution channels until existing supplies are depleted. Availability may vary by presentation with last lot expected to expire in March 2029.
Being discontinued · October 20, 2026Lovenox, Injection, 100 mg/1 mL (NDC 0075-0623-00)
Sanofi-Aventis U.S. LLCDiscontinuation of the manufacture of the drug for the U.S. market. This decision is not related to product safety or quality concerns. FDA-approved generic enoxaparin products and other treatment options are available. Remaining inventory may continue to be available through wholesalers and other distribution channels until existing supplies are depleted. Availability may vary by presentation with last lot expected to expire in March 2029.
Being discontinued · October 20, 2026Enoxaparin Sodium, Injection, 40 mg/.4 mL (NDC 0955-1004-10)
Sanofi-Aventis U.S. LLCDiscontinuation of the manufacture of the drug for the U.S. market. This decision is not related to product safety or quality concerns. FDA-approved generic enoxaparin products and other treatment options are available. Remaining inventory may continue to be available through wholesalers and other distribution channels until existing supplies are depleted. Availability may vary by presentation with last lot expected to expire in March 2029.
Being discontinued · October 20, 2026Lovenox, Injection, 40 mg/.4 mL (NDC 0075-0620-40)
Sanofi-Aventis U.S. LLCDiscontinuation of the manufacture of the drug for the U.S. market. This decision is not related to product safety or quality concerns. FDA-approved generic enoxaparin products and other treatment options are available. Remaining inventory may continue to be available through wholesalers and other distribution channels until existing supplies are depleted. Availability may vary by presentation with last lot expected to expire in March 2029.
Being discontinued · October 20, 2026Enoxaparin Sodium, Injection, 300 mg/3 mL (NDC 0955-1016-01)
Sanofi-Aventis U.S. LLCDiscontinuation of the manufacture of the drug for the U.S. market. This decision is not related to product safety or quality concerns. FDA-approved generic enoxaparin products and other treatment options are available. Remaining inventory may continue to be available through wholesalers and other distribution channels until existing supplies are depleted. Availability may vary by presentation with last lot expected to expire in March 2029.
Being discontinued · October 20, 2026Enoxaparin Sodium, Injection, 80 mg/.8 mL (NDC 0955-1008-10)
Sanofi-Aventis U.S. LLCDiscontinuation of the manufacture of the drug for the U.S. market. This decision is not related to product safety or quality concerns. FDA-approved generic enoxaparin products and other treatment options are available. Remaining inventory may continue to be available through wholesalers and other distribution channels until existing supplies are depleted. Availability may vary by presentation with last lot expected to expire in March 2029.
Being discontinued · October 20, 2026Lovenox, Injection, 120 mg/.8 mL (NDC 0075-2912-01)
Sanofi-Aventis U.S. LLCDiscontinuation of the manufacture of the drug for the U.S. market. This decision is not related to product safety or quality concerns. FDA-approved generic enoxaparin products and other treatment options are available. Remaining inventory may continue to be available through wholesalers and other distribution channels until existing supplies are depleted. Availability may vary by presentation with last lot expected to expire in March 2029.
Being discontinued · October 20, 2026 -
Leuprolide Acetate Being discontinued 1 product · updated October 20, 2026
Oncology
Product Availability Expected supply / notes Leuprolide Acetate, Injection, 14 mg/2.8 mL (1 mg/0.2 mL) (NDC 70121-2537-6)
Amneal PharmaceuticalsA business decision was made to discontinue manufacture of the drug.
Being discontinued · October 20, 2026 -
Molnupiravir Being discontinued 3 products · updated October 20, 2026
Anti-Infective, Antiviral
Product Availability Expected supply / notes Lagevrio, Capsule, 200 mg (NDC 0006-5055-06)
Merck Sharp & Dohme LLCDiscontinuation of the manufacture of the drug
Being discontinued · October 20, 2026Lagevrio, Capsule, 200 mg (NDC 0006-5055-07)
Merck Sharp & Dohme LLCDiscontinuation of the manufacture of the drug
Being discontinued · October 20, 2026Lagevrio, Capsule, 200 mg (NDC 0006-5055-09)
Merck Sharp & Dohme LLCDiscontinuation of the manufacture of the drug
Being discontinued · October 20, 2026 -
Lamivudine Being discontinued 2 products · updated October 19, 2026
Antiviral
Product Availability Expected supply / notes Epivir, Tablet, 150 mg (NDC 49702-203-18)
ViiV Healthcare CompanyThe anticipated date that ViiV will cease distribution of the products is approximately April 15, 2027; Discontinuation of the manufacture of the drug
Being discontinued · October 19, 2026Epivir, Tablet, 300 mg (NDC 49702-204-13)
ViiV Healthcare CompanyThe anticipated date that ViiV will cease distribution of the products is approximately April 15, 2027; Discontinuation of the manufacture of the drug
Being discontinued · October 19, 2026 -
Vigabatrin Being discontinued 1 product · updated October 16, 2026
Neurology
Product Availability Expected supply / notes Vigabatrin, Tablet, 500 mg (NDC 0054-0652-25)
Hikma Pharmaceuticals USA, Inc.The decision to discontinue this drug product was due to a business decision and not due to any reasons of safety or effectiveness.
Being discontinued · October 16, 2026 -
Dexmedetomidine Being discontinued 2 products · updated October 14, 2026
Anesthesia
Product Availability Expected supply / notes Dexmedetomidine Hydrochloride, Injection, 200 mcg/2 mL (NDC 83634-600-02)
Jiangsu Hengrui Pharmaceuticals Co. (US Agent eVenus Pharmaceutical Laboratories, Inc.)Discontinuation of the manufacture of the drug; Distributed by Avenacy; Contact information: 877-283-6229
Being discontinued · October 14, 2026Dexmedetomidine Hydrochloride, Injection, 100 ug/1 mL (NDC 16729-239-93)
Accord Healthcare Inc.Discontinuation of the manufacture of the drug
Being discontinued · April 21, 2026 -
Everolimus Being discontinued 15 products · updated October 14, 2026
Transplant
Product Availability Expected supply / notes Everolimus, Tablet, 1 mg (NDC 49884-283-02)
Par Health, USA LLCA business decision was made to withdraw from sale.
Being discontinued · October 14, 2026Everolimus, Tablet, .5 mg (NDC 49884-159-02)
Par Health, USA LLCA business decision was made to withdraw from sale.
Being discontinued · October 14, 2026Everolimus, Tablet, .25 mg (NDC 49884-158-02)
Par Health, USA LLCA business decision was made to withdraw from sale.
Being discontinued · October 14, 2026Everolimus, Tablet, .75 mg (NDC 49884-160-02)
Par Health, USA LLCA business decision was made to withdraw from sale.
Being discontinued · October 14, 2026Everolimus, Tablet, 10 mg (NDC 0093-7769-24)
Teva Pharmaceuticals USA, Inc.Discontinuation of the manufacture of the drug
Being discontinued · March 2, 2026Everolimus, Tablet, 7.5 mg (NDC 0093-7768-24)
Teva Pharmaceuticals USA, Inc.Discontinuation of the manufacture of the drug
Being discontinued · March 2, 2026Everolimus, Tablet, 5 mg (NDC 0093-7767-24)
Teva Pharmaceuticals USA, Inc.Discontinuation of the manufacture of the drug
Being discontinued · March 2, 2026Everolimus, Tablet, 2.5 mg (NDC 0093-7766-24)
Teva Pharmaceuticals USA, Inc.Discontinuation of the manufacture of the drug
Being discontinued · March 2, 2026Everolimus, Tablet, 2.5 mg (NDC 49884-119-91)
Endo Pharmaceuticals, Inc.Discontinuation of the manufacture of the drug
Being discontinued · January 6, 2026Everolimus, Tablet, 5 mg (NDC 49884-125-91)
Endo Pharmaceuticals, Inc.Discontinuation of the manufacture of the drug
Being discontinued · January 6, 2026Everolimus, Tablet, 10 mg (NDC 49884-128-91)
Endo Pharmaceuticals, Inc.Discontinuation of the manufacture of the drug
Being discontinued · January 6, 2026Everolimus, Tablet, 7.5 mg (NDC 49884-127-91)
Endo Pharmaceuticals, Inc.Discontinuation of the manufacture of the drug
Being discontinued · January 6, 2026Everolimus, Tablet, 2 mg (NDC 0378-0005-85)
Mylan Pharmaceuticals Inc., a Viatris CompanyDiscontinuation of the manufacture of the drug
Being discontinued · November 3, 2025Everolimus, Tablet, 5 mg (NDC 0378-0007-85)
Mylan Pharmaceuticals Inc., a Viatris CompanyDiscontinuation of the manufacture of the drug
Being discontinued · November 3, 2025Everolimus, Tablet, 3 mg (NDC 0378-0006-85)
Mylan Pharmaceuticals Inc., a Viatris CompanyDiscontinuation of the manufacture of the drug
Being discontinued · November 3, 2025 -
Felodipine Being discontinued 6 products · updated October 7, 2026
Cardiovascular
Product Availability Expected supply / notes Felodipine, Tablet, Extended Release, 2.5 mg (NDC 0603-3581-21)
Par Health, USA LLCDiscontinuation in the manufacturing of the drug product
Being discontinued · October 7, 2026Felodipine, Tablet, Extended Release, 2.5 mg (NDC 0603-3581-28)
Par Health, USA LLCDiscontinuation in the manufacturing of the drug product
Being discontinued · October 7, 2026Felodipine, Tablet, Extended Release, 5 mg (NDC 0603-3582-21)
Par Health, USA LLCDiscontinuation in the manufacturing of the drug product
Being discontinued · October 7, 2026Felodipine, Tablet, Extended Release, 5 mg (NDC 0603-3582-28)
Par Health, USA LLCDiscontinuation in the manufacturing of the drug product
Being discontinued · October 7, 2026Felodipine, Tablet, Film Coated, Extended Release, 10 mg (NDC 0603-3583-21)
Par Health, USA LLCDiscontinuation in the manufacturing of the drug product
Being discontinued · October 7, 2026Felodipine, Tablet, Film Coated, Extended Release, 10 mg (NDC 0603-3583-28)
Par Health, USA LLCDiscontinuation in the manufacturing of the drug product
Being discontinued · October 7, 2026 -
Fluocinonide Being discontinued 3 products · updated October 2, 2026
Dermatology
Product Availability Expected supply / notes Fluocinonide, Ointment, .5 mg/1 g (NDC 0093-0264-92)
Teva Pharmaceuticals USA, Inc.Discontinuation of the manufacture of the drug
Being discontinued · October 2, 2026Fluocinonide, Ointment, .5 mg/1 g (NDC 0093-0264-30)
Teva Pharmaceuticals USA, Inc.Discontinuation of the manufacture of the drug
Being discontinued · October 2, 2026Fluocinonide, Ointment, .5 mg/1 g (NDC 0093-0264-15)
Teva Pharmaceuticals USA, Inc.Discontinuation of the manufacture of the drug
Being discontinued · October 2, 2026 -
Ivermectin Being discontinued 1 product · updated September 29, 2026
Anti-Infective
Product Availability Expected supply / notes STROMECTOL, Tablet, 3 mg (NDC 0006-0032-01)
Merck Sharp & Dohme LLCProduct will be discontinued on 10/31/2026
Being discontinued · September 29, 2026 -
Arsenic Trioxide Being discontinued 2 products · updated September 21, 2026
Oncology
Product Availability Expected supply / notes Arsenic Trioxide, Injection, 1 mg/1 mL (NDC 63323-637-10)
Fresenius Kabi USA, LLCDiscontinuation of the manufacture of the drug
Being discontinued · September 21, 2026Arsenic Trioxide, Injection, 1 mg/1 mL (NDC 50742-438-10)
Ingenus Pharmaceuticals LLCA business decision was made to discontinue manufacture of the drug.
Being discontinued · February 24, 2026 -
Rivaroxaban Being discontinued 1 product · updated September 18, 2026
Hematology
Product Availability Expected supply / notes Xarelto, For Suspension, 155 mg (NDC 50458-575-01)
Janssen PharmaceuticalsBusiness Decision
Being discontinued · September 18, 2026 -
Rivastigmine Being discontinued 1 product · updated September 18, 2026
Neurology
Product Availability Expected supply / notes Rivastigmine, Film, Extended Release, 4.6 mg/24 h (NDC 0378-9070-93)
Mylan Pharmaceuticals Inc., a Viatris CompanyDiscontinuation of the manufacture of the drug.
Being discontinued · September 18, 2026 -
Melphalan Hydrochloride Being discontinued 1 product · updated September 16, 2026
Oncology
Product Availability Expected supply / notes Melphalan Hydrochloride, Injection, Kit (NDC 63323-760-20)
Fresenius Kabi USA, LLCDiscontinuation of the manufacture of the drug
Being discontinued · September 16, 2026 -
Mesalamine Being discontinued 3 products · updated September 16, 2026
Gastroenterology
Product Availability Expected supply / notes Pentasa, Capsule, Extended Release, 250 mg (NDC 54092-189-81)
Takeda Pharmaceuticals USA Inc.Product is anticipated to be available until December 31, 2027
Being discontinued · September 16, 2026Pentasa, Capsule, Extended Release, 500 mg (NDC 54092-191-12)
Takeda Pharmaceuticals USA Inc.Product is anticipated to be available until December 31, 2027
Being discontinued · September 16, 2026Mesalamine, Capsule, Extended Release, .375 g (NDC 0378-1375-78)
Mylan Pharmaceuticals Inc., a Viatris CompanyDiscontinuation of the manufacture of the drug
Being discontinued · August 25, 2026 -
Cisatracurium Besylate Being discontinued 3 products · updated September 11, 2026
Analgesia/Addiction
Product Availability Expected supply / notes Cisatracurium Besylate, Injection, 10 mg/5ml (2 mg/mL) Single Dose Vial (NDC 0409-1098-02)
Hospira, Inc., a Pfizer CompanySupply expected to exhaust November 2026; Discontinuation of the manufacture of the drug
Being discontinued · September 11, 2026Cisatracurium Besylate, Injection, 20 mg/10 mL (2 mg/mL) Multidose Vial (NDC 0409-1208-01)
Hospira, Inc., a Pfizer CompanySupply expected to exhaust late June 2026; Discontinuation of the manufacture of the drug
Being discontinued · May 6, 2026Cisatracurium Besylate, Injection, 200 mg/20ml (10 mg/mL) Single Dose Vial (NDC 0409-1103-01)
Hospira, Inc., a Pfizer CompanySupply expected to exhaust late June 2026; Discontinuation of the manufacture of the drug
Being discontinued · May 6, 2026 -
Micafungin Sodium Being discontinued 2 products · updated September 11, 2026
Anti-Infective
Product Availability Expected supply / notes Micafungin Sodium, Injection, 10 mg/1 mL (NDC 42023-229-10)
Par Health, USA LLCA business decision was made to discontinue manufacture of the drug.
Being discontinued · September 11, 2026Micafungin Sodium, Injection, 20 mg/1 mL (NDC 42023-230-10)
Par Health, USA LLCA business decision was made to discontinue manufacture of the drug.
Being discontinued · September 11, 2026 -
Dextrose Monohydrate, Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride Being discontinued 1 product · updated September 10, 2026
Renal
Product Availability Expected supply / notes DELFLEX, Solution, 18.4 mg/100 mL; 4.25 g/100 mL; 5.08 mg/100 mL; 538 mg/100 mL; 448 mg/100 mL (NDC 46163-212-95)
Fresenius Medical Care North AmericaA business decision was made to discontinue manufacture of the drug.
Being discontinued · September 10, 2026 -
Imipenem Anhydrous, Cilastatin, and Relebactam Anhydrous Being discontinued 1 product · updated September 9, 2026
Anti-Infective
Product Availability Expected supply / notes RECARBRIO, Injection, 500 mg/100 mL; 500 mg/100 mL; 250 mg/100 mL (NDC 0006-3856-02)
Merck Sharp & Dohme LLCTo be discontinued on or near late September 2026.
Being discontinued · September 9, 2026 -
Glycerol Phenylbutyrate Being discontinued 2 products · updated September 1, 2026
Inborn Errors
Product Availability Expected supply / notes RAVICTI, Oral Liquid, 1.1 g/1 mL (NDC 75987-050-06)
Amgen Inc.Discontinuation in the manufacturing of the drug product
Being discontinued · September 1, 2026RAVICTI, Oral Liquid, 1.1 g/1 mL (NDC 75987-050-07)
Amgen Inc.Discontinuation in the manufacturing of the drug product
Being discontinued · September 1, 2026 -
Insulin Glargine Being discontinued 1 product · updated September 1, 2026
Endocrinology/Metabolism
Product Availability Expected supply / notes Rezvoglar, Injection, 100 [iU]/1 mL (NDC 0002-8980-05)
Eli Lilly and Co.A business decision was made to discontinue manufacture of the drug. Distribution projected to end June 2027. If patients or prescribers have any questions, the Lilly Answers Center (1-800-545-5979) is available Monday through Friday from 9am to 8pm for assistance.
Being discontinued · September 1, 2026 -
Insulin Lispro Being discontinued 2 products · updated September 1, 2026
Endocrinology/Metabolism
Product Availability Expected supply / notes Insulin Lispro Junior KwikPen, Injection, 100 [iU]/1 mL (NDC 0002-7752-05)
Eli Lilly and Co.A business decision was made to discontinue manufacture of the drug. Distribution projected to end June 2027. If patients or prescribers have any questions, the Lilly Answers Center (1-800-545-5979) is available Monday through Friday from 9am to 8pm for assistance.
Being discontinued · September 1, 2026Humalog Mix 75/25, Injection, 100 [iU]/1 mL (NDC 0002-8233-05)
Eli Lilly and Co.A business decision was made to discontinue manufacture of the drug. Distribution projected to end June 2027. If patients or prescribers have any questions, the Lilly Answers Center (1-800-545-5979) is available Monday through Friday from 9am to 8pm for assistance.
Being discontinued · September 1, 2026 -
Medroxyprogesterone Acetate Being discontinued 2 products · updated August 31, 2026
Urology
Product Availability Expected supply / notes PROVERA, Tablet, 2.5 mg (NDC 0009-0065-01)
Pfizer Inc.Discontinuation of the manufacture of the drug; Withdrawal from sale expected early October 2026.
Being discontinued · August 31, 2026PROVERA, Tablet, 10 mg (NDC 0009-0051-01)
Pfizer Inc.Discontinuation of the manufacture of the drug; Withdrawal from sale expected September 2026.
Being discontinued · August 31, 2026 -
Metoprolol Succinate Being discontinued 7 products · updated August 31, 2026
Cardiovascular
Product Availability Expected supply / notes Metoprolol Succinate, Tablet, Extended Release, 50 mg (NDC 45963-676-11)
Teva Pharmaceuticals USA, Inc.A business decision was made to discontinue manufacture of the drug.
Being discontinued · August 31, 2026Metoprolol Succinate, Tablet, Extended Release, 100 mg (NDC 45963-677-11)
Teva Pharmaceuticals USA, Inc.A business decision was made to discontinue manufacture of the drug.
Being discontinued · August 31, 2026Metoprolol Succinate, Tablet, Extended Release, 200 mg (NDC 45963-678-11)
Teva Pharmaceuticals USA, Inc.A business decision was made to discontinue manufacture of the drug.
Being discontinued · August 31, 2026Metoprolol Succinate, Tablet, Extended Release, 50 mg (NDC 45963-676-96)
Teva Pharmaceuticals USA, Inc.A business decision was made to discontinue manufacture of the drug.
Being discontinued · August 31, 2026Metoprolol Succinate, Tablet, Extended Release, 100 mg (NDC 45963-677-96)
Teva Pharmaceuticals USA, Inc.A business decision was made to discontinue manufacture of the drug.
Being discontinued · August 31, 2026Metoprolol Succinate, Tablet, Extended Release, 25 mg (NDC 45963-709-96)
Teva Pharmaceuticals USA, Inc.A business decision was made to discontinue manufacture of the drug.
Being discontinued · August 31, 2026Metoprolol Succinate, Tablet, Extended Release, 25 mg (NDC 45963-709-11)
Teva Pharmaceuticals USA, Inc.A business decision was made to discontinue manufacture of the drug.
Being discontinued · August 31, 2026 -
Palovarotene Being discontinued 1 product · updated August 31, 2026
Musculoskeletal
Product Availability Expected supply / notes SOHONOS, Capsule, 2.5 mg (NDC 15054-0025-1)
Ipsen Biopharmaceuticals, Inc.Discontinuation of the manufacture of the drug
Being discontinued · August 31, 2026 -
Potassium Chloride Being discontinued 5 products · updated August 31, 2026
Cardiovascular, Endocrinology/Metabolism, Gastroenterology
Product Availability Expected supply / notes Cardioplegic Solution, Injection, Solution, 17.6 mg/100 mL; 325.3 mg/100 mL; 119.3 mg/100 mL; 643 mg/100 mL (NDC 65219-258-10)
Fresenius Kabi USA, LLCDiscontinuation of the manufacture of the drug
Being discontinued · August 31, 2026Potassium Chloride, Tablet, Extended Release, 20 meq (NDC 62037-720-10)
Teva Pharmaceuticals USA, Inc.Discontinuation of the manufacture of the drug
Being discontinued · November 21, 2025Potassium Chloride, Tablet, Extended Release, 20 meq (NDC 62037-720-05)
Teva Pharmaceuticals USA, Inc.Discontinuation of the manufacture of the drug
Being discontinued · November 21, 2025Potassium Chloride, Tablet, Extended Release, 20 meq (NDC 62037-720-01)
Teva Pharmaceuticals USA, Inc.Discontinuation of the manufacture of the drug
Being discontinued · November 21, 2025Potassium Chloride, Tablet, Extended Release, 10 meq (NDC 62037-710-01)
Teva Pharmaceuticals USA, Inc.Discontinuation of the manufacture of the drug
Being discontinued · November 21, 2025 -
Liraglutide Being discontinued 2 products · updated August 25, 2026
Endocrinology/Metabolism
Product Availability Expected supply / notes Saxenda, Injection, 6 mg/1 mL (NDC 0169-2800-15)
Novo Nordisk, Inc.Product will be available until discontinuation in January 2027; Discontinuation of the manufacture of the drug
Being discontinued · August 25, 2026Liraglutide, Injection, 6 mg/1 mL (NDC 0480-7250-46)
Teva Pharmaceuticals USA, Inc.Discontinuation of the manufacture of the drug
Being discontinued · May 14, 2026 -
Disopyramide Phosphate Being discontinued 2 products · updated August 24, 2026
Cardiovascular
Product Availability Expected supply / notes Norpace CR, Capsule, Extended Release, 100 mg (NDC 0025-2732-31)
Pfizer Inc.Discontinuation of the manufacture of the drug
Being discontinued · August 24, 2026Norpace CR, Capsule, Extended Release, 150 mg (NDC 0025-2742-31)
Pfizer Inc.Discontinuation of the manufacture of the drug
Being discontinued · August 24, 2026
Reading the list: a medicine stays on the FDA list while any of its products is short. "Available" next to a product means that particular strength or pack can currently be ordered. If your pharmacy cannot fill a prescription, ask the pharmacist or prescriber about another strength, form or an alternative — do not ration or stop a medicine on your own.
Source: FDA Drug Shortages Database, via openFDA. Updated here twice a day; last update October 31, 2026 14:40. openFDA data are not validated for clinical use — confirm with the FDA source or your pharmacist.